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M94A2576.TXT
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Document 2576
DOCN M94A2576
TI Increasing trend in HIV-1 prevalence among STD heterosexual females:
data from the National Sentinel Surveillance System. STD Surveillance
Working Group.
DT 9412
AU Giuliani M; Suligoi B; Centro Operativo AIDS-Istituto Superiore di
Sanita, Roma, Italy.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):272 (abstract no. PC0008). Unique
Identifier : AIDSLINE ICA10/94369999
AB OBJECTIVES: To monitor HIV-1 seroprevalence in heterosexual patients
seen in the sentinel STD clinical network in Italy. METHODS: All STD
patients seen in one of the 47 participating centers, after providing
informed consent, were tested for anti HIV-1 antibodies. Behavioral and
clinical data were collected using a standardized data collection form.
RESULTS: From September 1990 through December 1992, 10,797 heterosexual
STD patients, no I.V.D.Us., were tested for anti-HIV-1; 3929 (36.4%)
were females. Two hundred thirty seven patients (2.2%) were HIV-1
seropositive (150 males, 87 females). Overall HIV-1 seropositivity was
associated with a history of previous STDs (OR = 2.3: IC95%: 1.7-3.1),
only in females, with incident herpes genitalis infection (OR = 3.1
IC95%: 1.6-5.8). Quarterly data demonstrated that the HIV-1
seroprevalence rose in the total population from 1.4% in September 1990
to 2.3 in December 1992. Most of the increase was due to an increase in
seroprevalence among females. In this group, HIV-1 seroprevalence
increased during the study period from 1.4 to 2.8 (chi-square for trend:
7.6 p = 0.005). CONCLUSIONS: The data show an increase of HIV-1
infection among STD female population. The increasing of prevalence of
HIV-1 infection is consistent with an increase of the proportion of AIDS
cases reported among females in Italy. The role of herpes genitalis
infection in the acquisition of HIV-1 in our population, needs to be
further examined through longitudinal studies.
DE Female Human *HIV Seroprevalence *HIV-1 Italy/EPIDEMIOLOGY Male
Population Surveillance Prevalence Sexually Transmitted
Diseases/COMPLICATIONS/EPIDEMIOLOGY/ *MICROBIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).